Native Human Cathepsin G

Molecule:

Cathepsin G

Synonyms:

CG

Species:

Human

Cat. No.:

CSI19629B pdf (datasheet)

Quantity/Size:

10 mg

Price:

$1,750.00 BUY

Description:

Human Cathepsin G (CTSG) is a serine protease, and a member of the peptidase S1 protein family, located in the azurophil granules of neutrophils. Studies have shown that CTSG when released from granulocytes binds to NK cells and augments NK cytotoxicity through its protease activity. CTSG has a specificity similar to that of Chymotrypsin C, and may participate in the killing and digestion of engulfed pathogens, and in connective tissue remodeling at sites of inflammation. Transcript variants utilizing alternative polyadenylation signals exist for this gene.

Concentration:

≥ 1 mg/ml (Coomassie)

Entrez Symbol:

CTSG

Uniprot Name:

Cathepsin G

Uniprot ID:

P08311

Data PDF:

CSI19629

Source:

Human Neutrophils

Physical State:

Liquid

Formulation:

Sterile-filtered liquid in 50 mM sodium acetate, 0.8 M NaCl, pH 5.5

Purity:

> 90% by SDS-PAGE

Biological Activity:

≥ 5 U/ml, defined as 1 unit hydrolyzes 1 micromole of succinyl-alanine-alanine-proplinephenylalanine-p-nitroanilide per minute at 37°C at pH 7.5

Specific Activity:

≥ 5 U/mg protein

Storage/Stability:

Store at 2-8°C.