Native Human Platelet Factor 4

Molecule:

Platelet Factor 4

Synonyms:

CXCL4, C-X-C motif chemokine 4, Oncostatin-A, Iroplact

Species:

Human

Cat. No.:

CRP271A pdf (datasheet)

Quantity/Size:

100 μg

Price:

$495.00 BUY

Description:

Platelet Factor 4 (PF4) is a member of the CXC chemokine family. This chemokine is released from the alpha granules of activated platelets in the form of a homotetramer which has high affinity for heparin and is involved in platelet aggregation. This protein is chemotactic for numerous other cell type and also functions as an inhibitor of hematopoiesis, angiogenesis and T-cell function. The protein also exhibits antimicrobial activity against Plasmodium falciparum.

Concentration:

> 2.0 mg/mL

Entrez Symbol:

PF4

Uniprot Name:

Platelet factor 4

Uniprot ID:

P02776

Data PDF:

CRP271A

Source:

Human plasma

Molecular Weight:

29 kDa

Physical State:

Liquid

Formulation:

0.025 M HEPES, 2.0 M NaCl, pH 7.4.

Purity:

>95% by SDS-PAGE analysis

Specific Activity:

> 100 U/mg, defined as 1 unit will neutralize 1 U of heparin in 1 mL of normal plasma. Heparin-neutralizing activity is verified by clotting assay.

Storage/Stability:

Store at -80°C