Native Human Cystatin C

Molecule:

Cystatin C

Synonyms:

Cystatin-3, CST3, Gamma Trace, Neuroendocrine basic polypepide

Species:

Human

Cat. No.:

CSI19649A pdf (datasheet)

Quantity/Size:

100 ug

Price:

$275.00 BUY

Description:

Human Cystatin C is a serum protein present in all body fluids, that is filtered out of the blood by the kidneys. Human Cystatin C serves as a measure of kidney function. Human Cystatin C is produced steadily by all types of nucleated cells in the body. Human Cystain C's low molecular mass allows it to be freely filtered by the glomerular membrane in the kidney.Human cystatin C concentration in blood correlates with the glomerular filtration rate. Cystatin C is a marker for allograph function in adult transplant patients. Cystatin C regulates extracellular cysteine protease activity, which results from microbial invasion or release of lysosomal proteinases from dying or diseased cells. It is freely filtered by the glomerular basement membrane (GBM) and serum concentration has been shown to correlate well with glomerular filtration rate (GFR). A high level of Human cystatin C level in the blood after a heart attack reflects the failure of the kidney to clear human cystatin C from the blood into the urine.

Entrez Symbol:

CST3

Uniprot ID:

P01034

Data PDF:

CSI19649

Source:

Human urine from donors with chronic renal tubular proteinuria

Molecular Weight:

13 kDa

Formulation:

Lyophilized from 0.02 M ammonium bicarbonate

Purity:

> 96% SDS-PAGE

Storage/Stability:

Store at -20°C to -80°C for up to 1 year.