Synonyms:
Fragment D-dimer, Fibrin degradation product
Description:
D-dimer is a fibrin degradation product (FDP), a small protein fragment present in the blood after a blood clot is degraded by fibrinolysis. It is so named because it is comprised of two D fragments of the fibrin protein joined by a cross-link. The concentration of D-dimer may be determined by a blood test in order to help diagnose thrombosis.
Concentration:
1-5 mg/ml, by E 0.1% 280nm = 1.78
Molecular Weight:
~200 kDa
Formulation:
Sterile filtered solution of 0.05 M sodium phosphate, 0.15 M sodium chloride, 0.09% sodium azide, pH 7.5
Storage/Stability:
Centrifuge vial briefly to recover the entire contents. Store in working aliquots at -20°C to -80°C for up to 1 year. Avoid repeated freeze-thaw cycles.
