Native Human Hemoglobin A1c

Molecule:

HBA1c

Synonyms:

Hemoglobin subunit alpha 1, HbA1c, Glycohemoglobin, Glycated hemoglobin

Species:

Human

Cat. No.:

CSI14653B pdf (datasheet)

Quantity/Size:

100 μg

Price:

$325.00 BUY

Description:

Glycated hemoglobin (glycosylated hemoglobin, hemoglobin A1c, HbA1c, A1C, or Hb1c) is a form of hemoglobin which is measured primarily to identify the average plasma glucose concentration over prolonged periods of time. It is formed in a non-enzymatic glycation pathway by hemoglobin's exposure to plasma glucose to yield beta-N-1-deoxy fructosyl hemoglobin A1 Normal levels of glucose produce a normal amount of glycated hemoglobin. As the average amount of plasma glucose increases, the fraction of glycated hemoglobin increases in a predictable way. This serves as a marker for average blood glucose levels over the previous months prior to the measurement. The 2010 American Diabetes Association Standards of Medical Care in Diabetes added the A1c 48 mmol/mol (6.5%) as another criterion for the diagnosis of diabetes.

Concentration:

≥1.0 mg/ml

Entrez Symbol:

HBA1

Uniprot Name:

Hemoglobin subunit alpha

Uniprot ID:

P69905

Data PDF:

CSI14653

Source:

Human erythrocytes

Formulation:

0.05 M Sodium Phosphate, pH 8.0

Purity:

96% HbA1c as determined by quantitative analysis of HbA1c by FPLC using Mono S HbA1c column. Shows one band corresponding to hemoglobin molecular weight.

Endotoxin Level:

< 0.1 ng/µg of protein

Storage/Stability:

Store at -20°C to -80°C. Product is stable for 1 year from date of receipt, as supplied. On initial thaw, centrifuge vial to condense product, and store in working aliquots below -20° C. Avoid repeated freeze-thaw cycles.