Native Rabbit CK/creatine kinase

Molecule:

Creatine kinase

Synonyms:

CK, creatine phosphokinase, CPK

Species:

Rabbit

Cat. No.:

CSI14989A pdf (datasheet)

Quantity/Size:

1 KU

Price:

$235.00 BUY

Description:

Creatine kinase (CK) s an enzyme that consists of two subunits, which can be either B (brain type) or M (muscle type). Three different isoenzymes exist: CKBB, CKMM, and CKMB. This enzyme expressed by various tissues and cell types. Skeletal muscle expresses CKMM at 98%, CKMB at 1%. CK catalyses the conversion of creatine and consumes adenosine triphosphate (ATP) to create phosphocreatine (PCr) and adenosine diphosphate (ADP). This CK enzyme reaction is reversible, so that also ATP can be generated from PCr and ADP. Creatine kinase's clinical significance: detection of heart disease, liver disease, diseases of the central nervous system and thyroid disease.

Concentration:

> 0.6 mg protein/mg powder

Entrez Symbol:

CKM, CKB

Uniprot ID:

P00563 M-type, P00567 B-type

Data PDF:

CSI14989

Formulation:

Lyophilized from Tris-buffered saline, 1 mM DTT, pH 7.0

Biological Activity:

One Unit will transfer one mmole of phosphate from Creatine Phosphate to ADP per minute @ 37┬░C. Measured at 340 nm as one equimolar amount of NADH produced by a coupled reaction.

Specific Activity:

> 200 Units/mg protein (Dimension® Clinical Chemistry System)

Reconstitution:

Tris-buffered saline, 1 mM DTT, 1% BSA