Rabbit Anti-Human C3a Receptor 1 pAb

Molecule:

C3aR1

Synonyms:

C3a anaphylatoxin chemotactic receptor, C3aR

Species:

Human

Cat. No.:

CPC000 pdf (datasheet)

Quantity/Size:

200 μg

Price:

$280.00 BUY

Description:

C3a is an anaphylatoxin generated through activation of the complement C3. C3a is a potent chemoattractant for phagocytes, and it stimulates chemotaxis and other leukocyte functions. C3a binds to eosinophils, basophils, neutrophils, and differentiated U937 cells, that all express receptors for C3a on their cell surface. The C3a receptor has been cloned and shown to be a G protein-coupled receptor with seven putative transmembrane domains. This receptor is characterized for its large extracellular loop between the fourth and fifth transmembrane domains. The loop can be readily detected using the rabbit anti-C3a receptor antibody.

Entrez Symbol:

C3aR1

Uniprot Name:

C3a anaphylatoxin chemotactic receptor

Uniprot ID:

Q16581

Data PDF:

CPC000

Specificity:

Human C3aR

Host Species:

Rabbit

Immunogen:

E. coli-expressed human C3a receptor fragment (amino acids 161-332, corresponding to its second extracellular loop)

Isotype:

IgG

Conjugate:

Unconjugated

Formulation:

Lyophilized with 0.1% sodium azide.

Purification:

Protein A affinity chromatography

Reconstitution:

Centrifuge vial prior to opening. Reconstitute to 1 mg/ml by adding 200 µl sterile water.

Application:

FC, IHC

Storage/Stability:

Store at 2-8°C for short term storage. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freeze-thaw cycles.