Rabbit Anti-Human Fractalkine (Intracellular Domain) pAb

Molecule:

Fractalkine

Synonyms:

Neurotactin, C-X3-C motif chemokine 1, Small-inducible cytokine D1

Species:

Human

Cat. No.:

CPF201 pdf (datasheet)

Quantity/Size:

200 μg

Price:

$280.00 BUY

Description:

Fractalkine, also known as Neurotactin, is a membrane-bound CX3C chemokine. The mature protein is part of a 397-amino acid precursor and consists of a chemokine domain of 76 amino acids, a mucin stalk of 241 amino acids, a putative transmembrane domain of 18 amino acids, and an intracellular tail of 37 amino acids. Within the chemokine domain the first two cysteine residues are separated by 3 amino acids (CX3C). Fractalkine message is found in high abundance in the brain, kidney, lung and heart tissues. Fractalkine is chemotactic for monocytes and other leukocytes including NK cells, lymphocytes, and may play a role in brain inflammation.

Entrez Symbol:

CX3CL1

Uniprot Name:

Fractalkine

Uniprot ID:

P78423

Data PDF:

CPF201

Specificity:

Recombinant and Native Human Fractalkine

Host Species:

Rabbit

Immunogen:

E. coli-expressed intracellular domain (aa 379-397) of recombinant human fractalkine

Isotype:

IgG

Formulation:

Lyophilized with 0.1% Sodium Azide

Purification:

Protein A affinity chromatography

Reconstitution:

Centrifuge vial prior to opening. Reconstitute to 1 mg/mL by adding 200 µl sterile, distilled water.

Application:

WB

Application notes:

Western blot: 1:2,000

Storage/Stability:

Store at 2-8°C for short term or in working aliquots at -20°C to -80°C for long term storage. Avoid repeated freeze-thaw cycles.