Rabbit Anti-Human CX3CR1 pAb

Molecule:

CX3CR1

Synonyms:

CX3C chemokine receptor 1, Beta chemokine receptor-like 1, Fractalkine receptor, CMKBLR-1, G-protein coupled receptor 13, V28

Species:

Human

Cat. No.:

CPC200 pdf (datasheet)

Quantity/Size:

200 μg

Price:

$280.00 BUY

Description:

Fractalkine, also termed neurotactin, is a membrane-bound CX3C chemokine. Human CX3CR1, a G-protein coupled seven-transmembrane domain receptor, was identified to serve as a fractalkine receptor. Human CX3CR1 has been shown to mediate both the adhesive and migratory functions of fractalkine. Fractalkine and CX3CR1 represent new types of leukocyte trafficking regulators.

Entrez Symbol:

Cx3cr1

Uniprot Name:

CX3C chemokine receptor 1

Uniprot ID:

P49238

Data PDF:

CPC200

Specificity:

Reacts with recombinant and native human and rat CX3CR1

Host Species:

Rabbit

Immunogen:

E. coli-expressed human CX3CR1 amino terminal domain

Isotype:

IgG

Formulation:

Lyophilized with 0.05% sodium azide

Purification:

Protein A affinity chromatography

Reconstitution:

Centrifuge vial prior to opening. Add 200 µL sterile distilled water to the vial to fully solubilize the antibody to a concentration of 1.0 mg/mL.

Application:

IHC, WB

Application notes:

Western Blot: suggested working dilution of 1:1,000-1:2,000.

Neutralization (chemotaxis assay) : suggested working dilution of 15 µg/mL.

Immunohistochemistry: suggested working dilution of 1:100-1:500.

Storage/Stability:

Store as supplied at 2-8°C for short term. Prepare working aliquots and store at -20°C to -80°C for up to 1 year. Avoid repeated freeze-thaw cycles.