Rabbit Anti-Mouse Akt1/PKB pAb

Molecule:

PKB/Akt

Synonyms:

RAC-alpha serine/threonine-protein kinase, Akt1 kinase, Protein kinase B alpha, Protooncogene c-Akt

Species:

Mouse

Cat. No.:

CPA000 pdf (datasheet)

Quantity/Size:

200 μg

Price:

$280.00 BUY

Description:

Akt (also termed PKB, or RAC (Related to PKA and PKC), is the cellular homologue of the viral oncoprotein v-Akt. Akt is a serine / threonine kinases that consist of an Nterminal PH domain, a kinase domain and a C-terminal domain similar to that of the PKC family. Akta contains 480 amino acids, and can be activated by receptor tyrosine kinases through the PI 3-kinase pathway. Akt has been shown to suppress apoptosis. Recent study suggests that Akt may also be part of the NF-kB activation pathway.

Entrez Symbol:

Akt1

Uniprot Name:

RAC-alpha serine/threonine-protein kinase

Uniprot ID:

P31750

Data PDF:

CPA000

Specificity:

Mouse Akt/PKB

Host Species:

Rabbit

Immunogen:

E. coli-expressed mouse Akt-alpha (a.a. 375- 479)

Isotype:

IgG

Conjugate:

Unconjugated

Formulation:

Lyophilized with 0.1% sodium azide

Purification:

Protein A affinity chromatography

Reconstitution:

Centrifuge vial prior to opening. Reconstitute to 1 mg/ml by adding 200 ml H2O.

Application:

WB

Application notes:

Western blot: working dilution of 1:5,000.

Storage/Stability:

Store at 2-8°C for short term storage or -20°C to -80°C in working aliquots for long term storage. Avoid repeated freeze-thaw cycles.