Rabbit Anti-Mouse CX3CR1 (NT) Affinity Purified pAb

Molecule:

CX3CR1

Synonyms:

Fractalkine receptor, CCRL1, CMKBLR1, CMKDR1, GPR13, GPRV28, RBS11, V28

Species:

Human

Cat. No.:

PX168A pdf (datasheet)

Quantity/Size:

100 μg

Price:

$450.00 BUY

Concentration:

1 mg/ml

Description:

Rabbit Anti- CX3CR1 Affinity Purified polyclonal antibody. CX3CR1 is one of the chemokine receptors that are required as co-receptors for HIV infection. The genes encoding human, mouse, and rat CX3CR1 were cloned and designated V28 and CMKBRL1, CX3CR1, and RBS11, respectively. The encoded seven transmembrane protein was recently identified as the receptor for a novel transmembrane molecule, fractalkine, and renamed CX3CR1. Recently, CX3CR1 was found to serve as a coreceptor for HIV-1 and HIV-2 envelope fusion and virus infection, which can be inhibited by fractalkine. CX3CR1 mediates leukocyte migration and adhesion and is expressed in a variety of human tissues and cell lines.

Entrez Symbol:

CX3CR1

Uniprot Name:

CX3C chemokine receptor 1

Uniprot ID:

P49238

Data PDF:

PX168

Specificity:

Human, mouse, rat CXCR1

Host Species:

Rabbit

Immunogen:

20 amino acid peptide near the amino terminus of human CX3CR1. The immunogen is located within the first 50 amino acids of CX3CR1. The sequence differs from mouse and rat CX3CR1 by four amino acids.

Isotype:

IgG

Formulation:

PBS containing 0.02% sodium azide.

Purification:

Biospecific affinity chromatography

Application notes:

Western Blot: use at 0.5 - 1 μg/mL Human spleen tissue lysate can be used as positive control and an approximately 50 kDa band can be detected.

Flow Cytometry: use at 0.1 μg/ml

IHC-P: use at 2 μg/ml

IF: use at 10 μg/ml

The optimal concentration should be determined by the user for each specific application.

Storage/Stability:

Store at 2-8°C for up to 3 months. Prepare working aliquots and store at -20°C to -80°C for up to 1 year. Avoid repeated freeze/thaw cycles.