Rabbit Anti-Mouse CXCL12/SDF-1 alpha pAb

Molecule:

SDF-1alpha

Synonyms:

Stromal cell-derived factor 1 alpha, C-X-C motif chemokine 12, Pre-B-cell Growth Stimulating Factor, PBSF, Thymic lymphoma cell-stimulating factor, TLSF, TPAR1

Species:

Mouse

Cat. No.:

CPS000 pdf (datasheet)

Quantity/Size:

200 μg

Price:

$280.00 BUY

Description:

The rabbit polyclonal antibody recognizes mouse SDF-1α (stromal cell-derived factor-α), also known as pre-B-cell growth stimulating factor (PBSF). SDF-1α is a 70-amino acid CXC chemokine originally cloned from a bone marrow stromal cell line. Targeted deletion of SDF-1 gene resulted in defects of B-cell lymphopoiesis and bone marrow myelopoiesis. SDF-1 has been shown to be chemotactic for lymphocytes. In addition, SDF-1 was recently reported to be a ligand for CXCR4 (LESTR/fusin), a co-receptor for HIV-1 entry into T cells. SDF-1 binding to CXCR4 inhibits HIV-1 entry.

Entrez Symbol:

Cxcl12

Uniprot Name:

Stromal cell-derived factor 1

Uniprot ID:

P40224

Data PDF:

CPS000

Specificity:

Mouse SDF-1 α

Host Species:

Rabbit

Immunogen:

E. coli-expressed mouse SDF-1 α

Isotype:

IgG

Formulation:

Lyophilized with 0.1% sodium azide.

Purification:

Protein A affinity chromatography

Reconstitution:

Centrifuge vial prior to opening. Add 200 µL sterile distilled water to the vial to fully solubilize the antibody to a concentration of 1.0 mg/mL.

Cross Reactivity:

1440

Application:

IHC, WB

Application notes:

Western blot: working dilution of 1:1,000
Immunohistochemistry: working dilution of 1:100-1:500

Storage/Stability:

Store at 2-8°C as supplied for up to 1 year. Upon reconstitution, store working aliquots at -20°C to -80°C. Avoid repeated freeze-thaw cycles.