Rabbit Anti-Mouse Inhibitor of NF-kappa-B alpha pAb

Molecule:

NFKBIa

Synonyms:

I-kappa-B-alpha, IkB-alpha

Species:

Mouse

Cat. No.:

CPI200 pdf (datasheet)

Quantity/Size:

200 μg

Price:

$260.00 BUY

Description:

Purified Rabbit Anti-Mouse Inhibitor of NF-kappa-B alpha polyclonal antibody. IκBα protein is a NF-κB inhibitory protein. It binds NF-κB, retains the complex in the cytoplasm, prevents it from entering the nucleus, and functions as a transcription factor. Upon receiving a variety of signals, IκBα undergoes phosphorylation at serine residues by a ubiquitin-dependent protein kinase and is finally degraded by the proteasome. Free NFκB then binds to DNA and affects gene expression.

Entrez Symbol:

Nfkbia

Uniprot Name:

NF-kappa-B inhibitor alpha

Uniprot ID:

Q9Z1E3

Data PDF:

CPI200

Specificity:

Mouse Inhibitor of NF-kappa-B alpha

Host Species:

Rabbit

Immunogen:

E. coli expressed recombinant mouse IκBα

Isotype:

IgG

Conjugate:

Unconjugated

Formulation:

Lyophilized with 0.1% sodium azide

Purification:

Protein A affinity chromatography

Reconstitution:

Centrifuge vial prior to opening. Reconstitute to 1 mg/mL by adding 200 µL PBS

Application:

WB

Application notes:

Western Blot: working dilution of 1:2000

Storage/Stability:

Store at 2-8°C for short term or in working aliquots at -20°C to -80 °C for up to one year. Avoid repeated freeze-thaw cycles.