CX3CR1

CX3C chemokine receptor 1, Fractalkine receptor, RBS11

Rat

CPC408 pdf (datasheet)

200 μg

$280.00 BUY

Fractalkine, also termed neurotactin, is a membrane-bound CX3C chemokine. Rat CX3CR1, also named RBS11, was first cloned from rat brainstem, pituitary and/or spinal cord cDNA libraries. A G-protein-coupled seven-transmembrane domain receptor, it was recently identified to serve as fractalkine receptor. The human equivalent receptor is known as V28, which has been shown to mediate both the adhesive and migratory functions of fractalkine. Fractalkine and CX3CR1 represent new types of leukocyte trafficking regulators.

Cx3cr1

CX3C chemokine receptor 1

P35411

Recombinant and native rat CX3CR1

Rabbit

E. coli expressed rat CX3CR1 amino terminal domain

IgG

Lyophilized with 0.1% sodium azide.

Protein A affinity chromatography

Centrifuge vial prior to opening. Reconstitute to 1 mg/ml by adding 200 µl sterile, distilled water.

FC, IHC, WB

Western blot: suggested dilution 1:1,000-1:2,000

Immunohistochemistry: suggested dilution 1:100-1:300

Flow Cytometry: suggested dilution 1:100-1:300

Store at 2-8°C for short term or -20°C to 80°C in small aliquots for long term storage. Avoid repeated freeze/thaw cycles.