Rabbit Anti-Rat MIF pAb

Molecule:

MIF

Synonyms:

MIF, GIF, GLIF, MMIF

Species:

Rat

Cat. No.:

CPM300 pdf (datasheet)

Quantity/Size:

200 μg

Price:

$280.00 BUY

Description:

This polyclonal antibody recognizes Macrophage Migration Inhibitory Factor (MIF), one of the first cytokine activities to be discovered, initially described as a T cell-derived factor that inhibits the random migration of macrophages. Later, MIF was rediscovered as a pituitary hormone that acts as the counter-regulatory hormone for glucocorticoid action within the immune system. MIF is released from macrophages and T cells in response to physiological concentrations of glucocorticoids. Secreted MIF counter-regulates the immunosuppressive effects of steroids on immune cell activation and cytokine production. MIF plays a critical role in the host control of inflammation and immunity.

Entrez Symbol:

Mif

Uniprot Name:

Macrophage migration inhibitory factor

Uniprot ID:

P30904

Data PDF:

CPM300

Specificity:

Rat MIF

Host Species:

Rabbit

Immunogen:

E.coli-expressed full-length recombinant rat MIF

Isotype:

IgG

Formulation:

Lyophilized with 0.05% sodium azide

Purification:

Protein A affinity chromatography

Reconstitution:

Centrifuge vial prior to opening. Add 200 μl sterile distilled water to the vial to fully solubilize the antibody to a concentration of 1.0 mg/ml.

Application:

ELISA, IHC, Neutralizing , WB

Application notes:

Western blot: 1:2000
Immunohistochemistry: 1:500

Storage/Stability:

Store at 2-8 °C short term and in working aliquots at -20 °C for long term storage. Avoid repeated freeze-thaw cycles.