Rat Anti-Mouse VEGFA mAb

Molecule:

VEGFA

Synonyms:

Vegfa, Vpf, Vegf, Vegf120, Vegf164, Vegf188

Species:

Mouse

Cat. No.:

CMV105 pdf (datasheet)

Quantity/Size:

100 μg

Price:

$770.00 BUY

Description:

Mouse VEGF is a potent growth and angiogenic cytokine. It stimulates proliferation and survival of endothelial cells, and promotes angiogenesis and vascular permeability. Expressed in vascularized tissues, VEGF plays a prominent role in normal and pathological angiogenesis. Substantial evidence implicates VEGF in the induction of tumor metastasis and intra-ocular neovascular syndromes. VEGF signals through the three receptors; fms-like tyrosine kinase (flt-1), KDR gene product (the murine homolog of KDR is the flk-1 gene product) and the flt4 gene product.

Entrez Symbol:

Vegfa

Uniprot Name:

Vascular endothelial growth factor A

Uniprot ID:

Q00731

Data PDF:

CMV105

Specificity:

Recognizes mouse VEGF164 and VEGF120

Host Species:

Rat

Immunogen:

Recombinant murine VEGF-A (isoform 164), a 39.0 kDa disulfide-linked homodimeric protein consisting of two 164 amino acid polypeptide chains.

Isotype:

IgG2

Clone:

2G02

Formulation:

Lyophilized from a 0.2 µm sterile filtered solution in PBS

Purification:

Protein G affinity chromatography

Reconstitution:

Centrifuge vial prior to opening. Reconstitute in sterile ddH2O. The solution can then be further diluted in other aqueous buffers.

Application notes:

Optimal dilutions should be determined by each laboratory for each application.

Storage/Stability:

Store lyophilized antibody at -80°C