Recombinant Canine Animal Free IL-4

Molecule:

IL-4

Synonyms:

Canine IL-4, Interleukin-4, B-cell stimulatory factor-1, BSF-1, BCDF, BCGF

Species:

Canine

Cat. No.:

CS803A-AF pdf (datasheet)

Quantity/Size:

25 µg

Price:

$200.00 BUY

Description:

Interleukin 4 (IL-4) is an immunomodulatory cytokine that functions to induce naïve helper T cells to differentiate into type 2 T helper (Th2) cells. Th2 cells subsequently produce more IL-4 in a positive feedback loop. IL-4 also promotes immunoglobulin IgG to IgE isotype switching on B cells. IL-4 binds the IL-4Rα receptor to activate STAT6 signaling.

Manufactured without Animal-derived products, in an Animal Free facility.

Entrez Symbol:

IL4

Uniprot ID:

O77762

Data PDF:

CS803-AF

Source:

E. coli

Molecular Weight:

12.9 kDa (109 aa) monomer

Formulation:

Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 0.1% Trifluoroacetic Acid (TFA)

Purity:

≥ 95% by reducing and non-reducing SDS-PAGE

Biological Activity:

ED50 ≤ 25 ng/ml determined by TF-1 cell proliferation.

Specific Activity:

≥ 4.0 x 10e4 units/mg

Endotoxin Level:

≤ 1 EU/µg by kinetic LAL

Amino Acid Sequence:

MHNFNITIKE IIKMLNILTA RNDSCMELTV KDVFTAPKNT SDKEIFCRAA TVLRQIYTHN CSNRYLRGLY RNLSSMANKT CSMNEIKKST LKDFLERLKV IMQKKYYRH

Storage/Stability:

Lyophilized product is stable at room temperature for shipping purposes. Upon receipt, store at -20°C to -80°C for up to 1 year.