Recombinant Human Globular Adiponectin / gACRP30

Synonyms:

Adipocyte complement-related 30 kDa protein, ACRP30, Gelatin-binding protein, Adipocyte, C1q and collagen domain-containing protein

Species:

Human

Cat. No.:

CRA025D pdf (datasheet)

Quantity/Size:

100 μg

Price:

$435.00 BUY

Description:

Globular adiponectin, the globular C1q domain of adiponectin generated from full-length protein by naturally occurring proteolysis is biologically active. gACRP30 is detected at a relatively high concentrations in the serum and is thought to play an important role in hyperglycemia, insulin resistance and cognitive decline in obesity. gACRP30 signals through receptors, AdipoR1 and AdipoR2. T-cadherin as a receptor for hexameric and HMW forms of adiponectin.

Entrez Symbol:

ADIPOQ

Uniprot ID:

Q15848

Data PDF:

CRA025

Source:

E. coli

Molecular Weight:

Monomer, 16.7 kDa (145 aa)

Physical State:

Lyophilized

Formulation:

Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 10 mM sodium phosphate, 0.5 mM DTT, pH 7.5

Purity:

≥ 90% by reducing and non-reducing SDS-PAGE,

Biological Activity:

ED50 ≤ 2.0 µg/ml, determined by inhibition of M1 cell proliferation.

Specific Activity:

≥ 500 units/mg

Endotoxin Level:

≤ 1 EU/µg by kinetic LAL

Amino Acid Sequence:

MKGEPGEGAY VYRSAFSVGL ETYVTIPNMP IRFTKIFYNQ QNHYDGSTGK FHCNIPGLYY FAYHITVYMK DVKVSLFKKD KAMLFTYDQY QENNVDQASG SVLLHLEVGD QVWLQVYGEG ERNGLYADND NDSTFTGFLL YHDTN

Storage/Stability:

Store as supplied at -20°C to -80°C for up to 1 year.