Recombinant Human AKT1, Active, GST-tag

Molecule:

AKT1/PKB alpha

Synonyms:

RAC-alpha serine/threonine-protein kinase, Protein kinase B, PKB, Protein kinase B alpha, PKB alpha, Proto-oncogene c-Akt

Species:

Human

Cat. No.:

CRA004A pdf (datasheet)

Quantity/Size:

5 μg

Price:

$250.00 BUY

Description:

AKT1, a serine/threonine kinase that belongs to the AKT family, is activated in cells in response to diverse stimuli such as hormones, growth factors, and extracellular matrix components and is involved in glucose metabolism, transcription, survival, cell proliferation, angiogenesis, and cell motility. AKT1 is frequently overexpressed and active in many types of human cancers including cancers of colon, breast, brain, pancreas, and prostate as well as lymphoma and leukemia.

Concentration:

0.1 µg/µL

Entrez Symbol:

AKT1

Uniprot Name:

RAC-alpha serine/threonine-protein kinase

Uniprot ID:

P31749

EC number:

2.7.11.1

Data PDF:

CRA004

Source:

Sf9 insect cells

Molecular Weight:

~85 kDa

Tag:

GST

Physical State:

Liquid

Formulation:

50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM Glutathione, 0.1 mM EDTA, 0.1 mM PMSF, 25% Glycerol.

Purity:

> 95% by SDS-PAGE

Specific Activity:

Lot specific, > 100 nmol/min/mg using a synthetic peptide substrate (CKRPRAASFAE)

Storage/Stability:

Store in working aliquots at -80°C. Avoid repeated freeze-thaw cycles.

Application notes:

Assay protocol provided