Recombinant Human Apolipoprotein E3

Synonyms:

AD2, Apo-E, APOEA, Apolipoprotein E3

Species:

Human

Cat. No.:

CRA401A pdf (datasheet)

Quantity/Size:

50 μg

Price:

$235.00 BUY

Description:

Apolipoprotein E (Apo-E) belongs to a group of proteins that bind reversibly with lipoprotein and play an important role in lipid metabolism. In addition to facilitating solubilization of lipids, these proteins help to maintain the structural integrity of lipoproteins, serve as ligands for lipoprotein receptors, and regulate the activity of enzymes involved in lipid metabolism. Apo-E exists in three major isoforms; E2, E3, and E4, which differ from one another by a single amino-acid substitution. E3 is the most common isoform and is present in 40-90% of the population.

Recombinant human APOE3 contains 300 amino acid residues.

Source:

E. coli

Molecular Weight:

34.0 kDa

Formulation:

Sterile filtered and lyophilized from a buffer of 20 mM sodium phosphate

Purity:

>90% as determined by SDS-PAGE and HPLC analyses

Amino Acid Sequence:

MKVEQAVETE PEPELRQQTE WQSGQRWELA LGRFWDYLRW VQTLSEQVQE ELLSSQVTQE LRALMDETMK ELKAYKSELE EQLTPVAEET RARLSKELQA AQARLGADME DVCGRLVQYR GEVQAMLGQS TEELRVRLAS HLRKLRKRLL RDADDLQKRL AVYQAGAREG AERGLSAIRE RLGPLVEQGR VRAATVGSLA GQPLQERAQA WGERLRARME EMGSRTRDRL DEVKEQVAEV RAKLEEQAQQ IRLQAEAFQA RLKSWFEPLV EDMQRQWAGL VEKVQAAVGT SAAPVPSDNH

Storage/Stability:

Store lyophilized protein at -20°C