Recombinant Human BDNF Animal Free

Synonyms:

BDNF, Abrineurin, ANON2, BULN2

Cat. No.:

CRB600C-AF pdf (datasheet)

Quantity/Size:

1.0 mg

Price:

$6,260.00 / Special Price: $4,100.00 BUY

Description:

Brain Derived Neurotrophic Factor, or BDNF, is a nerve growth factor that supports neuron growth and survival. BDNF shares identical domains with two other neurotrophic factors known as, β-NGF and NT-3 (neurotrophin-3). BDNF binds with low affinity to a receptor known as LNGFR, which also binds NGF and NT-3, but mediates survival function by signaling through a high affinity receptor known as gp145/TrkB. Human, mouse, rat and pig BDNF are all cross-reactive. Recombinant human BDNF is a non-glycosylated homodimer, containing two 120 amino acid chains.

Entrez Symbol:

627

Uniprot ID:

P23560

Data PDF:

CRB600-AF

Source:

E. coli

Molecular Weight:

Homodimer (non-covalent), 13.6/27.3 kDa (120/240 aa)

Physical State:

Lyophilized

Formulation:

Lyophilized from a sterile filtered solution containing 0.1% Trifluoroacetic Acid (TFA).

Purity:

> 95% by reducing and non-reducing SDS-PAGE

Biological Activity:

As determined by the dose dependent proliferation of C6 cells, ED50 is 1.7 µg/mL

Specific Activity:

5.9 x 10e2 U/mg

Endotoxin Level:

≤ 1 EU/µg

Amino Acid Sequence:

MHSDPARRGE LSVCDSISEW VTAADKKTAV DMSGGTVTVL EKVPVSKGQL KQYFYETKCN PMGYTKEGCR GIDKRHWNSQ CRTTQSYVRA LTMDSKKRIG WRFIRIDTSC VCTLTIKRGR

Storage/Stability:

Store desiccated at -20 °C