Recombinant Human Nerve Growth Factor beta

Molecule:

NGF beta

Synonyms:

NGF, NGFB, HSAN5, Beta-NGF

Species:

Human

Cat. No.:

CRN117B pdf (datasheet)

Quantity/Size:

20 μg

Price:

$235.00 BUY

Description:

Nerve Growth Factor (NGF-beta) is a neurotrophic factor related to BDNF, NT-3 and NT-4. NGF-beta acts through its receptor beta-NGFR, and is involved in the development and maintenance of the sensory and sympathetic nervous systems. NGF-beta is also involved in the growth, differentiation and survival of B lymphocytes. Human, mouse and rat proteins show cross-reactivity.

Entrez Symbol:

NGF

Uniprot Name:

Beta-nerve growth factor

Uniprot ID:

P01138

Data PDF:

CRN117

Source:

E. coli

Molecular Weight:

Dimer, 13.6/27.3 kDa (121/242 aa)

Physical State:

Lyophilized

Formulation:

Sterile (0.2 micron) filtered aqueous solution containing 0.1% Trifluoroacetic Acid (TFA)

Purity:

≥95% determined by reducing and non-reducing SDS-PAGE.

Biological Activity:

ED50 ≤ 5.0 ng/mL, determined by its ability to stimulate the proliferation of TF-1 cells.

Specific Activity:

> 2.0 x 10e5 Units/mg

Endotoxin Level:

≤ 1 EU/μg by kinetic LAL analysis

Amino Acid Sequence:

MSSSHPIFHR GEFSVCDSVS VWVGDKTTAT DIKGKEVMVL GEVNINNSVF KQYFFETKCR DPNPVDSGCR GIDSKHWNSY CTTTHTFVKA LTMDGKQAAW RFIRIDTACV CVLSRKAVRR A

Storage/Stability:

Lyophilized protein is stable at room temperature for 3 weeks, but is preferably stored desiccated <-20℃C. After reconstitution, stable for 1 week at 2-4℃C. For long term storage, store at -20℃C with a carrier protein (0.1% HSA or BSA).