Recombinant Human BMP-2, Endotoxin Free

Synonyms:

BMP-2A, BMP2A

Cat. No.:

CRO506A pdf (datasheet)

Quantity/Size:

10 ug

Price:

$300.00 BUY

Description:

Human Bone Morphogenetic Protein 2 (BMP-2) is a member of the TGF-beta superfamily of cytokines that effect bone and cartilage formation. Human BMP-2 is a disulphide linked homodimeric protein. BMP-2 plays an important role in various processes during embryonic development, including induction of bone and cartilage growth and regeneration, cardiac cell differentiation and epithelial to mesenchymal transition. BMP2 promotes osteogenic and chondrogenic differentiation from mesenchymal cells, stem cells, and vascular smooth muscle cells. BMP-2 has great potentials for regenerative and medical therapeutic applications.

Data PDF:

CRO506

Source:

Tobacco

Molecular Weight:

Recombinant human BMP-2 produced in transgenic tobacco plants is a homodimeric polypeptide of 114 aa with a MW of 26 kDa

Formulation:

Lyophilized from a sterile solution of 25 mM MES, pH 6.0

Purity:

> 95% by SDS-PAGE gel analysis.

Biological Activity:

ED50 < 100 ng/ml, determined by the dose dependent induction of alkaline phosphatase production by ATDC-5 mouse chondrogenic cells.

Specific Activity:

> 1.0 x 10E-4