Recombinant Human BMP-4 active

Molecule:

BMP-4

Synonyms:

BMP4, BMP2B, BMP2B1, bone morphogenetic protein 4

Species:

Human

Cat. No.:

CRC404C pdf (datasheet)

Quantity/Size:

1 mg

Price:

$5,920.00 / Special Price: $3,880.00 BUY

Description:

BMP-4 is a member of the bone morphogenetic protein family which is part of the TGF-β superfamily of structurally related signaling proteins. Like other bone morphogenetic proteins, BMP-4 promotes bone and cartilage development, specifically tooth and limb development and fracture repair. BMP-4 is a critical signaling molecule required for early differentiation of the human embryo and establishing a dorsal ventral axis.

Entrez Symbol:

BMP4

Uniprot ID:

P12644

Source:

CHO cells

Molecular Weight:

13.1/26.2 kDa Dimer

Physical State:

Lyophilized

Formulation:

Sterile aqueous solution containing 0.1% TFA

Purity:

≥95% by reducing and non-reducing SDS-PAGE

Biological Activity:

ED50 ≤ 15 ng/ml, as determined by dose-dependent induction of alkaline phosphatase activity of ATDC-5 cells.

Specific Activity:

≥ 6.7 x 10e4 units/mg

Endotoxin Level:

≤1 EU/µg of protein by kinetic LAL

Amino Acid Sequence:

SPKHHSQRAR KKNKNCRRHS LYVDFSDVGW NDWIVAPPGY QAFYCHGDCP FPLADHLNST NHAI VQT LVN SVNSSIPKAC CVPTELSAIS MLYLDEYDKV VLKNYQEMVV EGCGCR

Storage/Stability:

Store as supplied at -20°C to -80°C for up to 1 year.