Recombinant Human TARC/CCL17

Molecule:

CCL17

Synonyms:

C-C motif chemokine 17, CC chemokine TARC, Thymus and Activation Regulated Chemokine, T cell-directed CC chemokine, Small-inducible cytokine A17, SCYA17

Species:

Human

Cat. No.:

CRT200C pdf (datasheet)

Quantity/Size:

1.0 mg

Price:

$2,720.00 / Special Price: $2,100.00 BUY

Description:

CCL17/TARC is one of several CC cytokines, proteins characterized by two adjacent cysteines. CCL17 displays chemotactic activity for T lymphocytes, but not monocytes or granulocytes. It binds to chemokine receptors CCR4 and CCR8. CCL17 plays important roles in T cell development in thymus as well as in trafficking and activation of mature T cells. CCL17 is constitutively expressed in thymus, and at a lower level in lung, colon, and small intestine. CCL17 is also transiently expressed in stimulated peripheral blood mononuclear cells.

Entrez Symbol:

CCL17

Data PDF:

CRT200

Source:

E. coli

Molecular Weight:

8.1 kDa (71 aa)

Formulation:

Lyophilized from a sterile-filtered solution containing 0.1% Trifluoroacetic Acid (TFA).

Purity:

> 95% by reducing and non-reducing SDS-PAGE

Endotoxin Level:

≤ 1 EU/µg of protein by kinetic LAL analysis

Amino Acid Sequence:

ARGTNVGREC CLEYFKGAIP LRKLKTWYQT SEDCSRDAIV FVTVQGRAIC SDPNNKRVKN AVKYLQSLER S

Reconstitution:

Centrifuge vial prior to opening. Add sterile distilled water to a concentration of 0.1 mg/ml. DO NOT VORTEX. Allow several minutes for complete reconstitution. Further dilutions should be made in appropriate buffered solutions.

Storage/Stability:

Store at -20°C to -80°C for up to 1 year