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Recombinant Human MIP-4/CCL18

Molecule:

CCL18

Synonyms:

C-C motif chemokine18, MIP-4, CCL18, AMAC-1, DC-CK1, small-inducible cytokine A18, SCYA18

Species:

Human

Cat. No.:

CRM410C pdf (datasheet)

Quantity/Size:

1.0 mg

Price:

$2,720.00 / Special Price: $2,100.00 BUY

Description:

Recombinant Human MIP-4/CCL18 is a single non-glycosylated polypeptide chain containing 69 amino acids.

Background: Human CCL18 is encoded by the CCL18 gene located on the chromosome 17. As also named MIP-4, it shares 61 % sequence identity to human MIP-1α. CCL18 is mainly expressed by lung and some lymphoid tissues such as lymph nodes. It is chemotactic for both activated (CD3+) T cells and nonactivated (CD14-) lymphocytes, but not for monocytes or granulocytes. CCL18 is involved in B-cell migration into B-cell follicles in lymph nodes. CCL18 plays a role in both humoral and cell-mediated immune responses.

Entrez Symbol:

CCL18

Uniprot Name:

C-C motif chemokine 18

Uniprot ID:

P55774

Source:

E. coli

Molecular Weight:

7.9 kDa (69 aa)

Physical State:

Lyophilized

Formulation:

Sterile filtered aqueous solution containing 0.1% Trifluoroacetic Acid (TFA).

Purity:

> 95% by reducing and non-reducing SDS-PAGE

Biological Activity:

This product demonstrates chemotaxis using primary human T cells.

Endotoxin Level:

≤1 EU/µg by kinetic LAL analysis

Amino Acid Sequence:

AQVGTNKELC CLVYTSWQIP QKFIVDYSET SPQCPKPGVI LLTKRGRQIC ADPNKKWVQK YISDLKLNA

Storage/Stability:

Store at -20°C to -80°C for up to 1 year.