Recombinant Human WISP-2 / CTGF-L

Molecule:

CTGF

Synonyms:

WNT1-inducible-signaling pathway protein 2, Connective tissue growth factor-like protein, CTGF-L, CCN family member 5

Species:

Human

Cat. No.:

CRC603C-AF pdf (datasheet)

Quantity/Size:

1.0 mg

Price:

$3,870.00 / Special Price: $3,160.00 BUY

Description:

WNT1-inducible-signaling pathway protein 2 (WISP-2) is a member of the CYR61/CTGF/NOV (CCN) family of regulatory factors. WISP-2 is expressed in ectodermal, mesodermal, and endodermal lineages, including primary osteoblasts, fibroblasts, mesenchymal stem cells, and adipogenic precursor cells. WISP-2 is a canonical WNT ligand that regulates cell proliferation, adhesion, and metastasis. Secreted WISP-2 promotes mesenchymal precursor cell proliferation and maintains them in an undifferentiated state. In bone-forming osteoblasts, WISP-2 promotes osteoblast adhesion and inhibits osteocalcin production.

This product is produced with no animal-derived raw materials.  All processing and handling employs animal-free equipment and animal-free protocols.

Entrez Symbol:

WISP2

Uniprot Name:

WNT1-inducible-signaling pathway protein 2

Uniprot ID:

O76076

Data PDF:

CRC603-AF

Source:

E. coli

Molecular Weight:

24.8 kDa (228 aa) monomer

Physical State:

Lyophilized

Formulation:

Sterile-filtered aqueous solution containing 0.1% Trifluoroacetic Acid (TFA)

Purity:

> 95% by reducing and non-reducing SDS-PAGE

Endotoxin Level:

< 1 EU/µg

Amino Acid Sequence:

MQLCPTPCTC PWPPPRCPLG VPLVLDGCGC CRVCARRLGE PCDQLHVCDA SQGLVCQPGA GPGGRGALCL LAEDDSSCEV NGRLYREGET FQPHCSIRCR CEDGGFTCVP LCSEDVRLPS WDCPHPRRVE VLGKCCPEWV CGQGGGLGTQ PLPAQGPQFS GLVSSLPPGV PCPEWSTAWG PCSTTCGLGM ATRVSNQNRF CRLETQRRLC LSRPCPPSRG RSPQNSAF

Reconstitution:

Centrifuge vial prior to opening. Add sterile distilled water to a concentration of 0.1 mg/mL and gently pipet the solution up and down the sides of the vial. DO NOT VORTEX. Allow several minutes for reconstitution. A small amount of precipitate may be seen.

Storage/Stability:

Store as supplied at -20°C to -80°C for up to 1 year. Upon reconstitution, prepare working aliquots and store at -20°C to -80°C. It is recommended that a carrier protein such as 0.1% HSA or BSA is added for long term storage.