Recombinant Human SDF-1 alpha/CXCL12

Molecule:

SDF-1 alpha

Synonyms:

Recombinant Staph V8 Glu-C Protease, Glutamyl endopeptidase, Endoproteinase Glu-C, Staphylococcal serine proteinase, V8 protease

Species:

Human

Cat. No.:

CRS000B pdf (datasheet)

Quantity/Size:

10 μg

Price:

$185.00 BUY

Description:

Glutamyl endopeptidase (Glu-C) is an enzyme from Staphylococcus aureus strain V8 that hydrolizes peptide bonds formed on the carboxyl terminal side of aspartate and glutamate amino acid residues. Glu-C is pathogenic to human tissue and functions during adherence and colonization of host cells. Glu-C protects against host defense mechanisms by fragmenting human immunoglobulins IgG, IgM, and IgA.

Entrez Symbol:

sspA

Uniprot Name:

Stromal cell-derived factor 1

Uniprot ID:

P0C1U8

Data PDF:

CRS000

Source:

E. coli

Molecular Weight:

Monomer, 28.9 kDa (267 aa)

Physical State:

Lyophilized

Formulation:

Lyophilized from a sterile-filtered solution containing 10 mM sodium phosphate, pH 7.5

Purity:

≥ 95% by reducing and non-reducing SDS-PAGE

Biological Activity:

Determined by a chemotaxis assy using activated human peripheral blood T-lymphocytes, typically in a concentration range of 10-75 ng/ml.

Endotoxin Level:

≤ 1 EU/µg by kinetic LAL analysis

Amino Acid Sequence:

MLPNNDRHQI TDTTNGHYAP VTYIQVEAPT GTFIASGVVV GKDTLLTNKH VVDATHGDPH ALKAFPSAIN QDNYPNGGFT AEQITKYSGE GDLAIVKFSP NEQNKHIGEV VKPATMSNNA ETQVNQNITV TGYPGDKPVA TMWESKGKIT YLKGEAMQYD LSTTGGNSGS PVFNEKNEVI GIHWGGVPNE FNGAVFINEN VRNFLKQNIE DIHFANDDQP NNPDNPDNPN NPDNPNNPDE PNNPDNPNNP DNPDNGDNNN SDNPDAA

Reconstitution:

Centrifuge vial prior to opening. Add sterile distilled water to a concentration of 0.1 mg/ml. DO NOT VORTEX. Allow several minutes for complete reconstitution.

Storage/Stability:

Lyophilized product is stable at room temperature for up to 3 weeks.