Recombinant Human FGF-17

Molecule:

FGF17

Synonyms:

FGF-17

Species:

Human

Cat. No.:

CRF009B pdf (datasheet)

Quantity/Size:

25 μg

Price:

$520.00 BUY

Description:

FGF-17 is a heparin binding growth factor that is a member of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-17 signals through the FGFR 1c, 2c, 3c, and 4. FGF-17 signals induction and patterning of embryonic brain.

Entrez Symbol:

FGF17

Uniprot Name:

fibroblast growth factor 17

Uniprot ID:

O60258

Data PDF:

CRF009B

Source:

E. coli

Molecular Weight:

22.7 kDa

Physical State:

Lyophilized

Formulation:

Lyophilized from 10 mM Tris, 30 mM NaCl, pH 8.0

Purity:

>95% by SDS-PAGE and HPLC analyses.

Biological Activity:

Assay #1: ED50 ≤ 0.5 ng/ml, determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF receptors. Assay #2: ED50 ≤ 10 ng/ml, determined by a cell proliferation assay using Balb/c 3T3 cells.

Specific Activity:

Assay #1: ≥ 2 x 106 units/mg Assay #2: ≥ 1 x 105 units/mg

Endotoxin Level:

< 1 EU/µg

Amino Acid Sequence:

MTQGENHPSP NFNQYVRDQG AMTDQLSRRQ IREYQLYSRT SGKHVQVTGR RISATAEDGN KFAKLIVETD TFGSRVRIKG AESEKYICMN KRGKLIGKPS GKSKDCVFTE IVLENNYTAF QNARHEGWFM AFTRQGRPRQ ASRSRQNQRE AHFIKRLYQG QLPFPNHAEK QKQFEFVGSA PTRRTKRTRR PQPLT

Storage/Stability:

Store at -20°C to -80°C.