Recombinant Human FGF-4

Molecule:

FGF4

Synonyms:

HBGF-4, HST, HST-1, HSTF1, K-FGF, KFGF

Species:

Human

Cat. No.:

CRF003C pdf (datasheet)

Quantity/Size:

1 mg

Price:

$3,200.00 / Special Price: $2,100.00 BUY

Description:

Fibroblast Growth Factor 4 (FGF-4) is a growth factor predominantly expressed during embryonic development, playing a key role in limb development. In culture, FGF-4 has been shown to be an important regulator of growth for stem cells, fibroblasts and endothelial cells. Unglycosylated FGF-4 is N-terminally cleaved into 13 kDa or 15 kDa proteins that are more active than the precursor 19 kDa protein, Bellosa P, et al. (1993). Human FGF-4 shares high homology and cross-reactivity with the mouse protein. Recombinant human FGF-4 is a non-glycosylated protein containing 140 amino acids.

Entrez Symbol:

FGF4

Data PDF:

CRF003

Source:

E. coli

Molecular Weight:

15 kDa

Physical State:

Sterile filtered white lyophilized (freeze-dried) powder.

Formulation:

Recombinant human FGF-4 is lyophilized with 0.5 x PBS, pH 7.5.

Purity:

Greater than 98% determined by: Reducing and Non-reducing SDS-PAGE.

Biological Activity:

The activity is determined by its ability to induce the proliferation of mouse NR6R 3T3 fibroblasts and is typically 0.25-1.25 ng/mL.

Endotoxin Level:

Measured by kinetic LAL analysis and is typically ≤ 1 EU/μg protein

Amino Acid Sequence:

AAVQSGAGDY LLGIKRLRRL YCNVGIGFHL QALPDGRIGG AHADTRDSLL ELSPVERGVV SIFGVASRFF VAMSSKGKLY GSPFFTDECT FKEILLPNNY NAYESYKYPG MFIALSKNGK TKKGNRVSPT MKVTHFLPRL

Reconstitution:

When reconstituting the product, gently pipet and wash down the sides of the vial to ensure full recovery of the protein into solution. It is recommended to reconstitute with sterile water at a concentration of 0.1 mg/mL

Storage/Stability:

Store at -20°C