Synonyms:
HBGF-6, HST-2, HSTF-2, heparin secretory-transforming protein 2, heparin-binding growth factor 6, FGF-6
Description:
Background: The FGFs play key roles in controlling tissue growth, morphogenesis and repair in animals. FGF-6 is a newly discovered heparin binding growth factor that stimulates the proliferation and activation of cells that express FGF receptors. Product
Uniprot Name:
fibroblast growth factor 6
Molecular Weight:
18.7 kDa
Physical State:
Lyophilized
Formulation:
Lyophilized from a sterile filtered solution without additives.
Purity:
>95% by SDS-PAGE and HPLC analyses.
Biological Activity:
ED50: 0.5-1.0 ng/ml (As determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF-receptors). For most in vitro applications, FGF-6 exerts its biological activity in the concentration range of 0.1 to 20.0 ng/ml.
Endotoxin Level:
<0.1 ng/�g
Reconstitution:
Centrifuge vial prior to opening. Reconstitute in sterile in 10 mM Sodium Phosphate, pH 7.2 + 50 mM NaCl to a concentration of >1 mg/ml. The solution can then be further diluted in water or other aqueous buffers.
Storage/Stability:
Lyophilized protein is stable at room temperature, but is preferably stored desiccated at<0℃C. After reconstitution, store at -20℃C. Avoid repeated freeze-thaw cycles.
