FGF-9

FGF-9, Glia-Activating Factor, GAF, Heparin-binding growth factor-9, HBFG-9

Human

CRF132C-AF pdf (datasheet)

1.0 mg

$3,870.00 / Special Price: $3,250.00 BUY

Fibroblast growth factor-9 (FGF-9) is a member of the fibroblast growth factor (FGF) family. All FGF family members are heparin binding growth factors with a core 120 amino acid FGF domain that allows for a common tertiary structure. FGF-9 plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. This protein was isolated as a secreted factor that exhibits a growthstimulating effect on cultured glial cells. FGF-9 is a monomer and interacts with FGFR1, FGFR2, FGFR3 and FGFR4. The human FGF-9 shares 98 % a.a. sequence identity with mouse, rat, equine, porcine, and bovine FGF-9.

Made without animal-derived components in an animal-free facility.

FGF9

Fibroblast growth factor 9

P31371

CRF132-AF

E. coli

23.4 kDa (207 aa) monomer

Lyophilized from a sterile filtered (0.2 µm) solution of 10 mM sodium phosphate, 25 mM sodium chloride, 50 mM sodium sulfate, pH 7.5

≥ 95% by reducing and non-reducing SDS-PAGE

ED50 ≤ 2.0 ng/ml, determined by 3T3 cell proliferation.

≥ 5.0 x 10e5

≤ 1 EU/µg, determined by kinetic LAL

MPLGEVGNYF GVQDAVPFGN VPVLPVDSPV LLSDHLGQSE AGGLPRGPAV TDLDHLKGIL RRRQLYCRTG FHLEIFPNGT IQGTRKDHSR FGILEFISIA VGLVSIRGVD SGLYLGMNEK GELYGSEKLT QECVFREQFE ENWYNTYSSN LYKHVDTGRR YYVALNKDGT PREGTRTKRH QKFTHFLPRP VDPDKVPELY KDILSQS

Centrifuge vial prior to opening. Add sterile distilled water to a concentration of 0.1 mg/mL and gently pipette the solution up and down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution.

Store as supplied at -20°C to -80°C for up to 1 year. Upon reconstitution, prepare working aliquots and store at -20°C to -80°C. It is recommended that a carrier protein such as 0.1% HSA or BSA is added for long term storage. Avoid repeated freeze-thaw cycles.