Recombinant Human FGF-acidic

Molecule:

FGF1

Synonyms:

FGF1, HBGF-1, Beta-endothelial growth factor, ECGF-beta

Species:

Human

Cat. No.:

CRH303B pdf (datasheet)

Quantity/Size:

100 µg

Price:

$320.00 BUY

Description:

Acidic fibroblast growth factor (FGF-acidic), also known as FGF-1, is a potent inducer of DNA synthesis, cell proliferation, and has chemotactic activities. FGFacidic regulates cardiogenesis through protein kinase C signaling. FGF-acidic also functions as an insulin sensitizer and mediates adipose tissue remodeling. High serum levels of FGF-acidic are associated with type 2 diabetes mellitus (T2DM), suggesting a pathogenic role of FGF-acidic during T2DM.

Uniprot Name:

P05230

Data PDF:

CRH303

Source:

E. coli

Molecular Weight:

Monomer, 16 kDa (141 aa)

Physical State:

Lyophilized

Formulation:

Lyophilized from a sterile-filtered solution containing 10 mM sodium phosphate, 75 mM sodium chloride, pH 7.5

Purity:

≥95% by reducing and non-reducing SDS-PAGE

Biological Activity:

Activity measured in BALB/c 3T3 cell proliferation assay and typical ED50 is < 1 ng/mL

Specific Activity:

≥ 5.0 x 10e5 U/mg

Endotoxin Level:

≤1 EU/µg by kinetic LAL analysis

Amino Acid Sequence:

MFNLPPGNYK KPKLLYCSNG GHFLRILPDG TVDGTRDRSD QHIQLQLSAE SVGEVYIKST ETGQYLAMDT DGLLYGSQTP NEECLFLERL EENHYNTYIS KKHAEKNWFV GLKKNGSCKR GPRTHYGQKA ILFLPLPVSS D

Storage/Stability:

Store desiccated at -20°