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Fibroblast growth factor-21 (FGF-21) is a member of the FGF family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes. FGF-21 is a secreted endocrine factor that functions as a major metabolic regulator. FGF-21 stimulates the uptake of glucose in adipose tissue. Activity requires the presence of beta-klotho (KLB).
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