FGF-21

FGF-21, FGFL

Human

CRF159C-AF pdf (datasheet)

1.0 mg

$2,990.00 / Special Price: $2,510.00 BUY

Fibroblast growth factor-21 (FGF-21) is a member of the FGF family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes. FGF-21 is a secreted endocrine factor that functions as a major metabolic regulator. FGF-21 stimulates the uptake of glucose in adipose tissue. Activity requires the presence of beta-klotho (KLB).

Made without animal-derived components in an animal-free facility.

FGF21

Fibroblast growth factor 21

Q9NSA1

CRF159-AF

E. coli

19.5 kDa (182 aa) monomer

Lyophilized

Lyophilized from a sterile filtered solution containing 10 mM sodium phosphate, 100 mM sodium chloride, pH 7.5.

> 95% by reducing and non-reducing SDS-PAGE

ED50 ≤ 500 ng/ml, determined by proliferation of 3T3 cells with β-klotho and heparin

≥ 2.0 x 10e3 unit/mg

≤ 1 EUs/µg by kinetic LAL analysis.

MHPIPDSSPL LQFGGQVRQR YLYTDDAQQT EAHLEIREDG TVGGAADQSP ESLLQLKALK PGVIQILGVK TSRFLCQRPD GALYGSLHFD PEACSFRELL LEDGYNVYQS EAHGLPLHLP GNKSPHRDPA PRGPARFLPL PGLPPALPEP PGILAPQPPD VGSSDPLSMV GPSQGRSPSY AS

Centrifuge vial prior to opening. Add sterile distilled water to a concentration of 0.1 mg/mL and gently pipet the solution up and down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution.

Store as supplied at -20°C to -80°C for up to 1 year. Upon reconstitution, prepare working aliquots and store at -20°C to -80°C. It is recommended that a carrier protein such as 0.1% HSA or BSA is added for long term storage. Avoid repeated freeze-thaw cycles.