Recombinant Human GM-CSF, Endotoxin Free

Synonyms:

GMCSF, GM-CSF, CSF2, Pluripoietin-alpha

Cat. No.:

CRO504A pdf (datasheet)

Quantity/Size:

10 ug

Price:

$250.00 BUY

Description:

Granulocyte macrophage colony-stimulating factor (GM-CSF) is a hematopoietic growth factor produced by various cell types such as T and B cells, macrophages, endothelial cells and fibroblasts, in response to cytokine or inflammatory stimuli. GM-CSF stimulates the development of granulocytes and macrophages, and the proliferation and development of erythroid, megakaryocyte and eosinophil progenitors. It also enhances functional activity of mature hematopoietic cells. GM-CSF is of great clinical value in reconstitution of the hematopoietic system following cancer therapy or bone marrow transplantation.

Data PDF:

CRO504

Source:

Rice

Molecular Weight:

Recombinant human GM-CSF contains 127 aa with no amino acid tag. MW is 14 kDa without glycosylation, and about 26 kDa with glycosylation.

Formulation:

Lyophilized from PBS, pH 7.2, sterile filtered through a 0.2 ┬Ám filter.

Purity:

> 95% by SDS-PAGE gel analysis.

Biological Activity:

ED50 < 0.2 ng/ml, for the dose-dependent effect of human GM-CSF on proliferation of TF-1 cells.

Specific Activity:

> 5.0 x 10E-6