Recombinant Human IGFBP2

Molecule:

IGFBP2

Synonyms:

IGF-BP2, Insulin-like growth factor-binding protein 2

Species:

Human

Cat. No.:

CRI272B pdf (datasheet)

Quantity/Size:

20 μg

Price:

$520.00 BUY

Description:

IGF-BPs controls the distribution, function and activity of IGFs in various cell tissues and body fluids. Currently there are seven named IGF-BPs that form high affinity complexes with both IGF-I and IGF-II. IGF-BP2 is a cysteine-rich secreted protein produced by bone cells, and is most abundant in the brain. IGF-BP2 has been shown to inhibit IGF-II action in human breast and ovarian carcinoma cells. Recombinant human IGF-BP2 consistS of 289 amino acid residues including the IGF-BP domain and thyroglobulin type-I domain.

Entrez Symbol:

IGFBP2

Uniprot ID:

P18065

Data PDF:

CRI272B

Source:

Insect cells

Molecular Weight:

31.5 kDa (289 aa)

Formulation:

Lyophilized from PBS

Purity:

>98% by SDS-PAGE analysis.

Biological Activity:

Determined by its ability to inhibit IGF-I induced proliferation of FDC-P1 cells.

Amino Acid Sequence:

EVLFRCPPCT PERLAACGPP PVAPPAAVAA VAGGARMPCA ELVREPGCGC CSVCARLEGE ACQVYTPRCG QGLRCYPHPG SELPLQALVM GEGTCEKRRD AEYGASPEQV ADNGDDHSEG GLVENHVDST MNMLGGGGSA GRKPLKSGMK ELAVFREKVT EQHRQMGKGG KHHLGLEEPK KLRPPPARTP CQQELDQVLE RISTMRLPDE RGPLEHLYSL HIPNCDKHGL YNLKQCKMSL NGQRGECWCV NPNTGKLIQG APTIRGDPEC HLFYNEQQEA RGVHTQRMQ

Storage/Stability:

Stable for 1 year at -20°C to -80°C.