Recombinant Human IL-16 (121 a.a.)

Synonyms:

IL-16, Lymphocyte chemoattractant factor, LCF

Species:

Human

Cat. No.:

CRI163C pdf (datasheet)

Quantity/Size:

1 mg

Price:

$4,820.00 / Special Price: $3,940.00 BUY

Description:

Human Interleukin-16, cleaved from pro-Interleukin-16, has four isoforms. The IL16 gene is located on chromosome 15. Interleukin-16, the ligand for CD4, is produced by CD4+ and CD8+ T cells and functions as a chemoattractant for lymphocytes, monocytes, eosinophils, dendritic cells, and Langerhans cells. Additionally, IL-16 upregulates the expression of the interleukin 2 receptor (CD25), modulates T lymphocyte growth, and suppresses the replication of the human immunodeficiency virus (HIV) and simian immunodeficiency viruses (SIV). Human IL-16 shares 85% a.a. sequence identity with mouse IL-16.

Uniprot Name:

Pro-interleukin-16

Uniprot ID:

Q14005

Data PDF:

CRI163

Source:

E. coli

Molecular Weight:

13.4 kDa (130 aa) monomer

Formulation:

Lyophilized from a sterile filtered solution of 10 mM sodium phosphate, pH 7.5

Purity:

≥ 95% by reducing and non-reducing SDS-PAGE

Endotoxin Level:

< 1 EU/μg, determined by kinetic LAL analysis

Amino Acid Sequence:

MPDLNSSTDS AASASAASDV SVESTAEATV CTVTLEKMSA GLGFSLEGGK GSLHGDKPLT INRIFKGAAS EQSETVQPGD EILQLGGTAM QGLTRFEAWN IIKALPDGPV TIVIRRKSLQ SKETTAAGDS

Reconstitution:

Centrifuge vial prior to opening. Add sterile distilled water to a concentration of 0.1 mg/mL and gently pipette the solution up and down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution.

Storage/Stability:

Store as supplied at -20°C to -80°C for up to 1 year. Upon reconstitution, prepare working aliquots and store at -20°C to -80°C. It is recommended that a carrier protein such as 0.1% HSA or BSA is added for long term storage. Avoid repeated freeze-thaw cycles.