Recombinant Human IL-17B

Molecule:

IL-17

Synonyms:

IL17B; NIRF; IL-20; IL-17B; Zcyto7

Species:

Human

Cat. No.:

CRI198B pdf (datasheet)

Quantity/Size:

25 μg

Price:

$520.00 BUY

Description:

IL-17B is a disulfide-linked homodimer of two 161 amino acid polypeptide chains. It belongs to the IL-17 family of structurally-related cytokines that share a highly conserved C-terminal region but differ from one another in their N-terminal regions and in their distinct biological roles. The six known members of this family, IL-17A through IL-17F, are secreted as homodimers. IL-17B is expressed by T-cells and has been shown to stimulate release of TNF-alpha and IL-1beta from cells of the monocyte lineage.

Entrez Symbol:

IL17B

Uniprot ID:

Q9UHF5

Data PDF:

CRI198B

Source:

E. coli

Molecular Weight:

36.6 kDa.

Formulation:

Sterile filtered and lyophilized from PBS, pH 7.5.

Purity:

>98% by SDS-PAGE and HPLC

Biological Activity:

Determined by its ability to induce IL-8 in human PBMCs using a concentration range of 10 ng-100 ng. Note: Results may vary with PBMC donors.

Amino Acid Sequence:

MQPRSPKSKR KGQGRPGPLA PGPHQVPLDL VSRMKPYARM EEYERNIEEM VAQLRNSSEL AQRKCEVNLQ LWMSNKRSLS PWGYSINHDP SRIPVDLPEA RCLCLGCVNP FTMQEDRSMV SVPVFSQVPV RRRLCPPPPR TGPCRQRAVM ETIAVGCTCI F

Storage/Stability:

Store as supplied at -20°C to -80°C for up to 1 year.