Synonyms:
IL-19, Melanoma differentiation-associated protein-like protein, NG.1
Description:
Human Interleukin 19 (IL-19) is a member of the IL-10 family of related cytokines.
IL-19 expression has been observed in keratinocytes and monocytes. IL-19 binds a
receptor complex consisting of IL-20 R alpha and the IL-20 R beta. This receptor
complex is also shared by IL-20 and IL-24.
Uniprot Name:
Interleukin-19
Molecular Weight:
17.9 kDa (154 aa) monomer
Formulation:
Lyophilized from a sterile filtered aqueous solution containing 0.1% Trifluoroacetic Acid
Purity:
≥ 95% by reducing and non-reducing SDS-PAGE.
Endotoxin Level:
≤ 1 EU/μg, determined by kinetic LAL analysis.
Amino Acid Sequence:
LRRCLISTDM HHIEESFQEI KRAIQAKDTF PNVTILSTLE TLQIIKPLDV CCVTKNLLAF YVDRVFKDHQ EPNPKILRKI SSIANSFLYM QKTLRQCQEQ RQCHCRQEAT NATRVIHDNY DQLEVHAAAI KSLGELDVFL AWINKNHEVM SSA
Reconstitution:
Centrifuge vial prior to opening. Add sterile distilled water to a concentration of 0.1 mg/mL and gently pipet the solution up and down the sides of the vial. DO NOT VORTEX. Allow several minutes for reconstitution.
Storage/Stability:
Store as supplied at -20°C to -80°C for up to 1 year. Upon reconstitution, prepare working aliquots and store at -20°C to -80°C. It is recommended that a carrier protein such as 0.1% HSA or BSA is added for long term storage. Avoid repeated freeze-thaw cycles.