Recombinant Human IL-2, Endotoxin Free

Molecule:

IL-2

Synonyms:

TCGF, T-cell growth factor, Aldesleukin

Species:

Human

Cat. No.:

CRI254A pdf (datasheet)

Quantity/Size:

10 μg

Price:

$210.00 BUY

Description:

Interleukin 2 (IL-2) is a potent immunoregulatory growth factor produced by T-cells following stimulation by mitogens or allogens. IL-2 promotes growth and differentiation of various cells of the immune system, such as activated T-cells and B-cells, NK cells, lymphokine activated killer cells, monocytes and macrophages. It is essential for proper immune response, it may also be an important factor in the natural suppression of autoimmunity. IL-2 may be of use as an anti-tumor agent in cancer therapy. Human and mouse IL-2 share 56% aa sequence identity and exhibit cross-species activity. The Recombinant Human IL-2 HQ contains 133 amino acids and a 16 a.a. histidine based tag for a total lenght of 149 a.a.

Data PDF:

CRI254

Source:

Barley

Molecular Weight:

Predicted MW = 17.5 kDa. The recombinant protein migrates with an apparent MW = 22

Formulation:

Lyophilized from a 0.2 ┬Ám sterile filtered solution of PBS, pH 7.2.

Purity:

>95% by SDS-PAGE

Biological Activity:

Bioactivity is assayed by measuring the dose dependent effect of human IL-2 on proliferation of CTLL-2 cells. The EC50 for a typical batch of recombinant human IL-2 is 1.08 ng/ml.

Specific Activity:

>1 x 10E-6 U/mg