Synonyms:
IL-20, Cytokine Zcyto10
Description:
Interleukin 20 (IL-20) is structurally related to interleukin 10 (IL-10) and is produced by
keratinocytes and monocytes. IL-20 acts through the STAT3 signaling pathway to
regulate the proliferation of keratinocytes during epidermal inflammation.
Uniprot Name:
Interleukin-20
Molecular Weight:
17.7/35.3 kDa (153/306 aa) dimer
Physical State:
Lyophilized
Formulation:
Lyophilized from sterile-filtered 10 mM sodium phosphate, 20 mM NaCl, pH 7.5
Purity:
≥ 95% by reducing and non-reducing SDS-PAGE
Endotoxin Level:
≤ 1 EU/μg, by kinetic LAL analysis
Amino Acid Sequence:
MLKTLNLGSC VIATNLQEIR NGFSEIRGSV QAKDGNIDIR ILRRTESLQD TKPANRCCLL RHLLRLYLDR VFKNYQTPDH YTLRKISSLA NSFLTIKKDL RLCHAHMTCH CGEEAMKKYS QILSHFEKLE PQAAVVKALG ELDILLQWME ETE
Reconstitution:
Centrifuge vial prior to opening. Add sterile distilled water to a concentration of 0.1 mg/mL and gently pipette the solution up and down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution.
Storage/Stability:
Store as supplied at -20°C to -80°C for up to 1 year. Upon reconstitution, prepare working aliquots and store at -20°C to -80°C. It is recommended that a carrier protein such as 0.1% HSA or BSA is added for long term storage. Avoid repeated freeze-thaw cycles.
