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Recombinant Human IL-3 Animal Free

Molecule:

IL-3

Synonyms:

MCGF, Multi-CSF, HCGF, P-cell stimulating factor

Species:

Human

Cat. No.:

CRH311C-AF pdf (datasheet)

Quantity/Size:

1 mg

Price:

$3,520.00 / Special Price: $2,300.00 BUY

Description:

Interleukin 3 is a cytokine that is produced by activated T cells and mast cells. IL-3 induces the differentiation of hematopoietic stem cells into myeloid precursor cells, such as erythrocyte, megakaryocyte, granulocyte, monocyte, and dendritic cells. IL-3 also functions in the nervous system and is important during the B-1 cell regulation of chronic inflammatory diseases.

Manufactured without Animal-derived products, in an Animal Free facility.

Entrez Symbol:

IL3

Uniprot Name:

Interleukin-3

Uniprot ID:

P08700

Data PDF:

CRH311-AF

Source:

E. coli

Molecular Weight:

Monomer, 15.2 kDa (134 aa)

Physical State:

Lyophilized

Formulation:

Sterile filtered (0.2 micron) aqueous solution containing 10 mM sodium phosphate, 150 mM sodium chloride, pH 7.5.

Purity:

≥95% by reducing and non-reducing SDS-PAGE

Biological Activity:

ED50 ≤ 2 ng/ml, determined by a dose-dependent TF-1 cell proliferation assay.

Specific Activity:

4.2 x 103 IU/μg, calibrated against recombinant human IL-3 WHO International Standard (NIBSC code: 91/510).

Endotoxin Level:

≤1 EU/µg by kinetic LAL analysis

Amino Acid Sequence:

MAPMTQTTPL KTSWVNCSNM IDEIITHLKQ PPLPLLDFNN LNGEDQDILM ENNLRRPNLE AFNRAVKSLQ NASAIESILK NLLPCLPLAT AAPTRHPIHI KDGDWNEFRR KLTFYLKTLE NAQAQQTTLS LAIF

Storage/Stability:

Store as supplied at -20°C to -80°C for up to 1 year.