Recombinant Human IL-5

Molecule:

IL-5

Synonyms:

B-cell differentiation factor I, Eosinophil differentiation factor, TRF

Species:

Human

Cat. No.:

CRH313C pdf (datasheet)

Quantity/Size:

1.0 mg

Price:

$4,020.00 / Special Price: $3,100.00 BUY

Description:

Interleukin 5 (IL-5) is a hematopoietic growth factor that is expressed in type 2 T helper (Th2) cells, mast cells, and eosinophils. IL-5 acts through the IL-5 receptor (IL-5R), stimulates B cell growth, and mediates eosinophil activation. Human and mouse IL-5 show cross-reactivity.

Entrez Symbol:

IL5

Uniprot Name:

Interleukin-5

Uniprot ID:

P05113

Data PDF:

CRH313

Source:

E. coli

Molecular Weight:

Dimer, 13.3/26.2 kDa (116/232 aa)

Physical State:

Lyophilized

Formulation:

Sterile-filtered solution containing 10 mM sodium glycinate, pH 8.5

Purity:

≥95% by reducing and non-reducing SDS-PAGE

Biological Activity:

ED50 ≤ 250 pg/ml, determined by inducing dose-dependent TF-1 cell proliferation.

Specific Activity:

≥ 4.0 x 106 U/mg

Endotoxin Level:

≤1 EU/µg by kinetic LAL analysis

Amino Acid Sequence:

MIPTEIPTSA LVKETLALLS THRTLLIANE TLRIPVPVHK NHQLCTEEIF QGIGTLESQT VQGGTVERLF KNLSLIKKYI DGQKKKCGEE RRRVNQFLDY LQEFLGVMNT EWIIES

Storage/Stability:

Store as supplied at -20°C to -80°C for up to 1 year.