Recombinant Human/Mouse Indian Hedgehog

Synonyms:

HHG-2

Cat. No.:

CRH310C pdf (datasheet)

Quantity/Size:

1.0 mg

Price:

$2,960.00 / Special Price: $1,940.00 BUY

Description:

Indian hedgehog (IHH) is an essential signaling factor that is secreted in the gut, cartilage, and bone during embryonic development. IHH acts through the patched (PTC) receptor to induce transcriptional changes important for bone and cartilage development. IHH also induces the expression of parathyroid hormone-related peptide (PTHrP), which in turn mediates IHH activity during chondrocyte differentiation, forming a negative feedback loop. Human and murine Indian Hedgehog proteins have 100% sequence homology.

Uniprot ID:

Q14623

Data PDF:

CRH310

Source:

E. coli

Molecular Weight:

Monomer, 19.9 kDa (177 aa)

Physical State:

Lyophilized

Formulation:

Lyophilized from a sterile-filtered solution containing 0.1% Trifluoroacetic Acid (TFA)

Purity:

≥95% by reducing and non-reducing SDS-PAGE

Endotoxin Level:

≤1 EU/µg by kinetic LAL analysis

Amino Acid Sequence:

MIIGPGRVVG SRRRPPRKLV PLAYKQFSPN VPEKTLGASG RYEGKIARSS ERFKELTPNY NPDIIFKDEE NTGADRLMTQRCKDRLNSLA ISVMNQWPGV KLRVTEGWDE DGHHSEESLH YEGRAVDITT SDRDRNKYGL LARLAVEAGF DWVYYESKAH VHCSVKSEHSAAAKTGG

Storage/Stability:

Store at -20 °C