Recombinant Human Insulin-Like Growth Factor Binding Protein 5

Molecule:

IGFBP5

Synonyms:

IGFBP-5, IGF-binding protein 5, IBP-5

Species:

Human

Cat. No.:

BP5BU020 pdf (datasheet)

Quantity/Size:

20 μg

Price:

$290.00 BUY

Description:

Human Insulin-like growth factor binding protein-5 (IGFBP-5) is a 252 amino acid protein which is a member of a family of six circulating proteins that bind IGF-I and IGF-II with high affinity and modulate their metabolic and mitogenic effects. Human IGFBP-5 preferentially binds to IGF-II and primarily inhibits the effects of IGF peptides. It can also form a ternary complex with the acid-labile sub-unit. It binds to extra-cellular matrix proteins which protect it from proteolysis and modify its biological functions. IGFBP-5 may also elicit a biological action through a non-IGF binding mechanism.

Entrez Symbol:

IGFBP5

Uniprot Name:

Insulin-like Growth Factor Binding Protein 5

Uniprot ID:

P24593

Data PDF:

BP5BU020

Source:

Mammalian cells

Molecular Weight:

Glycosylated IGFBP-5 is 28 kDa Non-glycosylated IGFBP-4 is 28.5 kDa

Physical State:

Lyophilized

Formulation:

Lyophilized from 0.1 M acetic acid under dry nitrogen at a slight vacuum (-25 kPa).

Purity:

> 95% as determined by FPLC and SDS-PAGE analysis

Endotoxin Level:

< 0.1 EU/μg

Reconstitution:

See Protocol 1100, Handling of IGF Binding Proteins 1-6

Storage/Stability:

Store at 2-8°C.