Recombinant Human IP-10 / CXCL10

Synonyms:

CXCL10, CRG-2

Cat. No.:

CRH314C pdf (datasheet)

Quantity/Size:

1.0 mg

Price:

$3,200.00 / Special Price: $2,100.00 BUY

Description:

Interferon gamma-induced protein 10 (IP-10), or CXCL10, is a chemokine secreted by monocytes, endothelial cells and fibroblasts in response to interferon gamma (IFN-ɣ). IP-10 functions as a chemoattractant for activated T cells, monocytes, dendritic, and natural killer (NK) cells that express the G protein-coupled receptor CXCR3. IP-10 is an important factor in autoimmune diseases such as Hashimoto's thyroiditis, Graves' disease, and Type 1 diabetes mellitus.

Uniprot ID:

P02778

Data PDF:

CRH314

Source:

E. coli

Molecular Weight:

Monomer, 8.6 kDa (77 aa)

Formulation:

Lyophilized from a sterile-filtered solution containing 0.1% Trifluoroacetic Acid

Purity:

≥95% by reducing and non-reducing SDS-PAGE

Biological Activity:

Bioactive, however; no acceptance criteria established

Endotoxin Level:

≤1 EU/µg by kinetic LAL analysis

Amino Acid Sequence:

VPLSRTVRCT CISISNQPVN PRSLEKLEII PASQFCPRVE IIATMKKKGE KRCLNPESKA IKNLLKAVSK ERSKRSP

Storage/Stability:

Store at -20 °C