Recombinant Human KGF/FGF7, Endotoxin Free

Molecule:

FGF7

Synonyms:

KGF, Keratinocyte Growth Factor, HBGF-7, FGF-7

Species:

Human

Cat. No.:

CRK107A pdf (datasheet)

Quantity/Size:

10 μg

Price:

$265.00 BUY

Description:

Fibroblast Growth Factor 7 is a member of the FGF family of 23 related mitogenic proteins. These proteins play a central role during embryonic development and postnatal growth and tissue repair, by promoting cellular proliferation and differentiation. KGF specifically stimulates epithelial cells and keratinocytes, it is the most potent growth factor identified thus far for skin keratinocytes. KGF takes part in the development of kidney and lung, angiogenesis and has a key role in wound healing following skin injuries. It shows considerable species cross-reactivity (mouse, monkey, porcine cells) as the other members of the FGF family.

Data PDF:

CRK107

Source:

Barley

Molecular Weight:

Recombinant human FGF7 contains 164 amino acids and a 16 aa His-tag for a total length of 180 aa and has a predicted molecular mass of 21.2 kD. As a result of glycosylation, the recombinant protein migrates as two bands with an apparent molecular mass of

Formulation:

Lyophilized from a 0.2 ┬Ám sterile filtered solution of PBS, pH 7.2.

Purity:

>95% by SDS-PAGE gel analysis

Biological Activity:

ED50< 10 ng/ml. Bioactivity was determined by dose dependent effect on proliferation of 4MBr5 rhesus monkey epithelial cells.

Specific Activity:

> 1.0 x 10E-5 U/mg