Recombinant Human LIF, Endotoxin Free

Synonyms:

Differentiation-stimulating factor, D factor, Melanoma-derived LPL inhibitor (MLPLI).

Cat. No.:

CRO503A pdf (datasheet)

Quantity/Size:

10 ug

Price:

$200.00 BUY

Description:

LIF has the capacity to induce terminal differentiation in leukemic cells. Its activities include the induction of hematopoietic differentiation in normal and myeloid leukemia cells, the induction of neuronal cell differentiation, and the stimulation of acute-phase protein synthesis in hepatocytes. Human and mouse LIF share 78% homology and activities of LIF are not species-specific. Human LIF is active on mouse cells, but murine LIF is not active on human cells.

Data PDF:

CRO503

Source:

Barley

Molecular Weight:

Recombinant human LIF contains 180 amino acids and a 16 a.a. histidine-based tag for a total length of 196 a.a. and has a predicted molecular mass of 21.8 kDa.

Formulation:

Lyophilized from a 0.2 ┬Ám sterile filtered solution of PBS, pH 7.2.

Purity:

>98% by SDS-PAGE gel analysis.

Biological Activity:

ED50 < 0.3 ng/ml. The bioactivity of recombinant human LIF was determined by its ability to induce proliferation of TF-1 cells in a dose dependent manner

Specific Activity:

> 3.3 x 10E-6 units/mg