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Recombinant Human Lymphotactin/XCL1

Molecule:

Lymphotactin

Synonyms:

ATAC, LPTN, LTN, SCM-1, SCM-1a, SCM1, SCYC1, lymphotactin, small inducible cytokine subfamily C, member 1 (lymphotactin)

Species:

Human

Cat. No.:

CRL100B pdf (datasheet)

Quantity/Size:

20 μg

Price:

$235.00 BUY

Description:

Recombinant Human Lymphotactin is a single non-glycosylated polypeptide chain containing 92 amino acids.

Background: Lymphotactin is the only known member of the C-chemokine family and signals through the receptor XCR1, formally known as GPR5. The spleen shows the highest level of lymphotactin compared to peripheral leukocytes, lung, colon and small intestine. Lymphotactin is chemotactic towards lymphocytes but not towards monocytes or neutrophils.

Data PDF:

CRL100

Source:

E. coli

Molecular Weight:

~10.2 kDa

Formulation:

Lyophilized from a 0.2 μm filtered concentrated solution in 20 mM PB, pH 7.4, 150 mM NaCl.

Purity:

>98 % by SDS-PAGE and HPLC analyses.

Biological Activity:

Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human T-lymphocytes is in a concentration of 10-100 ng/ml.

Endotoxin Level:

Less than 1EU/μg of rHuLymphotactin/XCL1 as determined by LAL method.

Amino Acid Sequence:

GSEVSDKRTC VSLTTQRLPV SRIKTYTITE GSLRAVIFIT KRGLKVCADP QATWVRDVVR SMDRKSNTRN NMIQTKPTGT QQSTNTAVTL TG

Reconstitution:

Centrifuge vial prior to opening. Add sterile distilled water or aqueous buffer to a concentration of 0.1-1.0 mg/mL. Further dilutions should be made in appropriate buffered solutions.

Storage/Stability:

Stable at 2-8°C, but best kept desiccated -20°C. Upon reconstitution, stable for up to 1 week at 2-8°C. For longer term, store in working aliquots below -20°C. Avoid repeated freeze/thaw cycles.