Recombinant Human MIP-1 alpha / CCL3

Molecule:

CCL3

Synonyms:

Macrophage inflammatory protein-1 alpha, C-C motif chemokine 3, CCL3, LD78 alpha, Small inducible cytokine A3

Species:

Human

Cat. No.:

CRH316C pdf (datasheet)

Quantity/Size:

1.0 mg

Price:

$2,720.00 / Special Price: $2,100.00 BUY

Description:

Macrophage inflammatory protein-1 alpha (MIP-1 α), also known as CCL3, is a cytokine produced by macrophages. MIP-1 α binds the chemokine receptors CCR1, CCR4 and CCR5 to induce inflammatory responses, including the recruitment of granulocytes and neutrophil superoxide production. The MIP-1 α and MIP-1 β heterodimer exhibits antiviral activity against the human immunodeficiency virus 1 (HIV-1).

Entrez Symbol:

CCL3

Uniprot Name:

C-C motif chemokine 3

Uniprot ID:

P10147

Data PDF:

CRH316

Source:

E. coli

Molecular Weight:

Monomer, 7.8 kDa (70 aa)

Formulation:

Lyophilized from a sterile-filtered solution containing 0.1% Trifluoroacetic Acid

Purity:

≥95% by reducing and non-reducing SDS-PAGE

Biological Activity:

This product demonstrates chemotaxis in assays with human PBMCs or THP-1 cells.

Endotoxin Level:

≤1 EU/µg by kinetic LAL analysis

Amino Acid Sequence:

ASLAADTPTA CCFSYTSRQI PQNFIADYFE TSSQCSKPGV IFLTKRSRQV CADPSEEWVQ KYVSDLELSA

Storage/Stability:

Store as supplied at -20°C to -80°C for up to 1 year.